RESEARCH AREA E
Clinical Translation
The area uses high-throughput molecular technologies from other research areas to establish a link between phenotypes and molecular signatures. Scientific goals include the reclassification of patient populations in a way that promotes faster diagnosis and a better direction of existing therapies.
Goals of the area include the clinical development of new therapies through clinical trials. Final goal is the development of novel, early interventions either in form of pre-emptive therapies or as preventive interventions.
Spotlight on facilities: The Comprehensive Center for Inflammation Medicine (CCIM) institutionalizes a novel interdisciplinary approach to chronic inflammatory barrier diseases. Specialists from different medical disciplines (dermatology, gastroenterology, hepatology, immunology, pneumonology, rheumatology) interact to define new diagnostic and therapeutic principles with general applicability to inflammatory disorders. They strive to establish a joint medical facility for advanced diagnosis and therapy of inflammatory disorders. Clinicians closely interact with the popgen biobank and a novel chair for (molecular and interventional) epidemiology.
Participating institutions: Universities Kiel and Lübeck (Medicine), Research Center Borstel
Spotlight on people: Clinical researchers who develop new drugs
Coordinators:
Stefan Schreiber (Gastroenterology), University Kiel
Phone: +49 431 5972350, E-Mail: Stefan Schreiber
Wolfgang Gross (Rheumatology), The "Rheumaklinik" of Bad Bramstedt
Phone: +49 4192 902575, E-Mail: Wolfgang Gross
University Lübeck
Phone: +049 451 2368, E-Mail: Wolfgang Gross
Junior Research Group I-e: Epithelial Protease Inhibitors
The role of novel antimicrobial protease inhibitors (API) shall be defined in healthy barrier organs and in inflammatory epithelial diseases. The use of APIs could be a therapeutic strategy for targeting proinflammatory exogenous proteases important for epithelial desquamation.
Coordinator:
Jens-Michael Schröder, University Kiel
Phone: +49 431 5971536, E-Mail: Jens-Michael Schröder
